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Hardcover Role of the Sarcoplasmic Reticulum in Smooth Muscle Book

ISBN: 0470844795

ISBN13: 9780470844793

Role of the Sarcoplasmic Reticulum in Smooth Muscle

(Part of the Novartis Foundation Symposia Series)

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a central role in smooth muscle function, increasing in concentration for contraction and decreasing for relaxation. Calcium entry into the cell is facilitated by the sarcoplasmic reticulum (SR).

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