Much of this text results from improved therapy for coronary artery disease, particularly acute myocardial infarction, for which the age adjusted mortality has declined by some 30% in the past 10 years. Accordingly, there has been increasing attention paid to congestive heart failure and there has been interest in developing new therapeutic approaches and modalities. The increasing interest in congestive heart failure has brought us an improved understanding of the pathophysiology of the condition, which, in turn, has permitted a more rational application of therapy. This monograph is designed to provide comprehensive information regarding the epidemiology, pathophysiology, diagnosis and treatment of congestive heart failure. It is hoped that this book will be valuable to primary care physicians, as well as cardiologists. The sections of the book dealing with treatment are designed to provide up-to-date information about the application and appropriate use of established and emerging therapies.
Table of Contents: *Epidemiology, Etiology, and Natural History - David McCall *Functional Properties of Normal and Failing Hearts - W. Gaasch & G. Freeman *Baroreflexes in Heart Failure - Toru Kinugawa & Marc Thames *Biochemical Abnormalities in Failing Heart - Joel Karliner *The Molecular Basis for Hypertrophic Growth of the Adult Heart - D. Mann & Robert Roberts *Neurohumoral Mechanisms in Heart Failure - G.S. Francis & Kenneth McDonald *Cardiovascular Tissue Angiotensin Systems: Activation and Actions in Heart Failure - A.T. Hirsch, M. Muellerleile, & V. Dzau *The Kidney and Heart Failure - G. Paradiso, G. Bakris, J. Stein *Evaluation of Left Ventricular Performance in Heart Failure - R. Applegate, T. Downes, W.C. Little *Exercise and Exercise Testing in Congestive Heart Failure - Louis Dell'Italia *Clinical Features, General Therapeutic Measures and Diuretics - D. McCall *Digitalis in Heart Failure - Shahbudin Rahimtoola & Tahir Tak *Newer Inotropic Agents - C.V. Leieur & P. Binkley *The Role of Vasodilator Therapy, Other than Angiotensin-Converting Enzyme Inhibition, in the Management of Chronic Congestive Heart Failure - J. Franciosa & R. McGarry *Treatment of Congestive Heart Failure with Angiotensin-Converting Enzyme Inhibitors - M. Creager & J. Cusco *Role of B-Adrenergic Blockers for the treatment of Congestive Heart Failure - E. Eichhorn *Ventricular Arrhythmias and Sudden Death in the Congestive Heart Failure - Simon Chakko & Robert Myerburg *Surgical Options for the Treatment of Cardiac Failure - Shukri F. Khuri, Patricia A. Lowry, & Nancy A. Healey *The Role of Cardiac Transplantation - Lynne Warner Stevenson
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