Vaccine Adjuvants

By Donald A. Harn Jr

Book Overview

A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

• Format: Hardcover
• Language: English
• ISBN: 0896038920
• ISBN13: 9780896038929
• Release Date: December 2005
• Publisher: Humana
• Length: 284 Pages
• Weight: 1.30 lbs.
• Dimensions: 0.7" x 6.1" x 9.2"