How can a gas found in car exhaust and city smog also keep your heart beating steadily, guard you against infection, help you form memories, and inspire the world's most famous little blue pill? This book tells the story of nitric oxide, a fragile molecule once dismissed as a pollutant and a reckless free radical. If you love biology, medicine, or a good scientific mystery, you will find it here.
Follow a rabbit aorta that refused to relax, a century-old heart remedy that worked without anyone knowing why, and three researchers, Robert Furchgott, Louis Ignarro, and Ferid Murad, who solved the riddle and shared the 1998 Nobel Prize. Discover how immune cells use nitric oxide as a weapon, how neurons use it to send messages backward, and how a failed angina drug became Viagra.
Written in the spirit of the best short introductions, this book needs no scientific background. Clear analogies, lively storytelling, and honest attention to controversy and chance turn complex biochemistry into a compelling human drama about how overturned assumptions can transform modern medicine.