Tetramer Stability and Functional Regulation of Tumor Suppressor Protein P53

By Rui Kamada

Book Overview

Quantitative analysis for p53 tetramerization domain mutants reveals a low threshold for tumor suppressor inactivation.- Stabilization of mutant tetrameric structures by calixarene derivatives.- Inhibition of the transcriptional activity of p53 through hetero-oligomerization.

• Format: Paperback
• Language: English
• ISBN: 4431547258
• ISBN13: 9784431547259
• Release Date: August 2014
• Publisher: Springer
• Length: 74 Pages
• Weight: 0.30 lbs.
• Dimensions: 0.2" x 6.1" x 9.2"