Structure-Based Drug Design: Thermodynamics, Modeling and Strategy

by J.E. Ladbury and Pat R. Connelly John E. Ladbury,J. E. Ladbury

This book connects two subjects: "drug design" - a biological science - and "thermodynamics" - a physical science. Armed with the knowledge of the three-dimensional structure of a potential binding site of a molecule, the method of structure-based design provides a rapid, rational route to a ligand molecule. Recent developments in the determination of structure and the measurement of thermodynamic parameters of binding have resulted in drawing theoretical...

• Format: Hardcover
• Language: English
• ISBN: 3540632506
• ISBN13: 9783540632504
• Release Date: October 1997
• Publisher: Springer
• Length: 188 Pages