Metabolic Autophagy: Metabolic Autophagy. The ultimate guide on intermittent fasting endurance training that helps you to build body and mu
Autophagy is a complex process that, when not working, is associated with the development of various diseases.
Imagine an entire city struggling with the waste collection strike. Just a few days, and its chaos, this could be the image to describe the process of autophagy, that complex cellular mechanism that leads to the elimination and recycling of many components within our body. When it does not work, many diseases appear.
When everything works, autophagy in adverse conditions guarantees cells both a rapid fuel and the raw material - deriving from the recycling of waste - to "build" new structures.
Autophagy is also fundamental in response to the attack of external agents, such as bacteria and viruses. Without it, the cell would be invaded by waste. When the mechanism is altered for various reasons, the cells undergo multiple disorders.
Several studies indicate that pathologies such as Parkinson's, diabetes and cancer can also derive from the failure of this complex system. Several rare genetic diseases are associated with mutations in those genes that regulate the autophagy process.
As for metabolism, a very effective way to increase cell life span, and therefore is a calorie restriction and controlled deprivation of energy.
Metabolism and Catabolism:
Metabolism is the complex of chemical transformations that take place in a cell, which allows a product to be obtained from a precursor molecule. The precursor, through single chemical reactions (the metabolic pathways), is transformed into intermediates that are called metabolites.
Catabolism is the "destructive" phase of metabolism, in which the organic nutrient molecules are broken down into simpler finished products. The catabolic pathways allow storing energy, coming from the breaking of the bonds of complex molecules, in high energy content molecules such as ATP.
if we create a balance between anabolic phase and body catabolic phase, we will obtain a scientifically proven effect on life span and aging.
The autophagy process involves the phagocyting by healthy cells on the old ones, to restore the energy process.
The energy thus obtained is used in the "constructive" phase of metabolism: anabolism. Anabolism, or biosynthesis, allows the synthesis of biomolecules, such as proteins, polysaccharides, nucleic acids, and lipids, starting from simple precursors.
In this book, you will find the above principles explained so that you can effectively apply them.
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