Immunogenicity of Biopharmaceuticals

by Marco van de Weert

Book Overview

A particular issue for biopharmaceuticals that has not been addressed comprehensively in any book, is the potential of an immune response to the biopharmaceutical product. That is, the human body marks the drug as a foreign body, and develops antibodies against the drug. These antibodies may be relatively harmless, but may also cross-react with the endogenous compound, causing autoimmunogenicity. Recent adverse experiences in Europe with Janssen-Ortho's...

• Format: Hardcover
• Language: English
• ISBN: 0387758402
• ISBN13: 9780387758404
• Release Date: March 2008
• Publisher: Springer
• Length: 266 Pages
• Weight: 0.90 lbs.
• Dimensions: 0.8" x 7.0" x 10.3"