An experimental pathologist and molecular genetieist, Philip Wooduses gene-knockout technology to study the way mouse genesregulate the metabolism of fat - research that provides insights into theworkings of fatty-acid metabolism in humans and what can happenwhen that metabolic balance goes awry. Based on the classes heregularly teaches to first- and second-year medical students, Wood'sbook reviews the individual and public health burden of obesity andclarifies often-used, but often inadequately explained, terms employedin the continuing cultural and scientific debate about excess fat. Heexplains the role of fat in the healthy body, how fat is made, stored andburned, and demonstrates how excess fat can lead to an array ofmetabolic disorders and diseases, from hypercholesterolemia andinsulin resistance to diabetes.
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