Histamine Intolerance Guide for Beginners Causes and Risk Factors of Histamine Intolerance Histamine intolerance is a complex and often misunderstood condition that involves the body's inability to adequately break down and eliminate histamine, leading to an accumulation of this chemical in the body. Histamine is a natural compound that is produced by the body and plays a crucial role in various physiological processes. It acts as a neurotransmitter, regulates stomach acid secretion, helps with immune responses, and plays a role in the sleep-wake cycle. Under normal circumstances, the body maintains a delicate balance of histamine levels through the activity of enzymes such as diamine oxidase (DAO) and histamine N-methyltransferase (HNMT), which break down histamine and ensure its proper elimination. However, individuals with histamine intolerance have deficiencies or dysfunctions in these enzymes, which results in an imbalance between histamine production and degradation. The exact cause of histamine intolerance is not fully understood, but there are several factors that may contribute to its development. One possible cause is a genetic predisposition, as some individuals may inherit variations in the genes responsible for histamine metabolism. GRAB YOUR COPY NOW
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