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Paperback Function of microRNAs in skeletal muscle cell differentiation Book

ISBN: 3736993064

ISBN13: 9783736993068

Function of microRNAs in skeletal muscle cell differentiation

Skeletal muscle cell differentiation is exogenously regulated by cytokines and growth factors and it is post-transcriptionally regulated by microRNAs (miRNAs). This study presents miRNA and gene expression data of differentiating skeletal muscles with or without concomitant TNF-alpha or IGF1 exposure to elucidate the function of miRNAs. Results indicate specific miRNA-target relations during skeletal muscle differentiation and show that miRNAs mediate the effect of TNF-alpha.

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