Essentials of Tissue Banking

By George Galea

Book Overview

Aparadigmshiftistakinginraisingstandardsonallaspectsoftissuebankingfrom procurementtoprocessing, fromstoragetoclinicalusage. Anumberofmonographs haveappearedgivingguidanceonGMPandqualitysystemsthatshouldbeadhered to. Therearealsogoodguidelinesonthesigni'canceofthenewregulationsthat havebeenenacted. However there is a signi'cant lack of information on the scienti'c basis and rationaleonwhytissuebankingpracticeshavedevelopedthewaytheyhave. Many ofthemhavedevelopedwithoutmuchvalidationandhavebeeninuseformany years, copied from one tissue bank to another. There are some good articles on somescienti'caspectsoftissuebankingpractices, buttheyareinrelativelyoldand insomewhatobscurejournals. Thisbookisintendedto'llthisgapbygettinga seriesofeminentexpertstoeachwriteachapterortwoonuptodatetissuebanking practices. Moreoverinthemodernworldoftissuebanking, safetyandqualityoftissues havetakenanincreasinglyimportantrole. Infacttheseactivitiesformthebasisof manylicensureactivitiesthatrelatetotissueestablishments. Anattempthasbeen madetocovertheseaspectsaswell. Althoughthelegislationcoversalltypesofcells, includingstemcells, theyhave beendeliberatelyomitted. Thetargetaudiencesforstemcellsaredifferentandthe setupisalsogenerallyquitedifferentunlikecordblood, whichisverysimilarto tissuesandthereforeincluded. Inordertolimitthesizeofthebooktoamanageableleveltheauthorshavebeen onlyaskedtocoverthebasisofcurrentpractices, ratherthanfuturedevelopments, suchasembryoniccelldevelopments, tissueengineeringandgenetherapy, which aremorecellulartherapiesthantissuebanking, perse. Coursesconferringcert- catesanddiplomashavejuststartedtobeprovidedbyvariousprofessionalbodies. Thisisimportantbecausetissuebankingisbecomingadistinctmodalityforsci- tistswhowanttoworkinthe'eld. Ibelievesuchanaudiencewouldbeverykeen tousethisbook. Alsoanyscientistandmedicalpersonworkinginthe'eldshould beinterestedinit. Itwillalsobeusefulformanysurgeonswhousetissuesintheir dailyclinicalpractice. Iamverygratefultoalltheauthors, whowithoutexceptionwillinglygaveso muchtime, effortandenergyinwritingtheirchapters. Theyarewithoutexception, v vi Preface leadersintheir'eld. Theyhaveallproduceduptodateandstateoftheartchapters. Theyhavedoneitinthestyletheyfeltwasappropriateandnoattemptwasmadeto modifythis. Thekeyobjectivewastocollateallthisinformationinoneplace. Ihave learntalotwhilsteditingthisworkandIhopethatthereaderswillbeengrossedin readingthisbookasmuchasIhave. Edinburgh, Scotland GeorgeGalea Contents Part I Management of 1 Live Donors of Tissue . . . . . . . . . . . . . . . . . . . . . . . . . 3 RuthWarwick 2 Deceased Donors of Tissue. . . . . . . . . . . . . . . . . . . . . . . 23 AuroraNavarro 3 Banking of Cord Blood. . . . . . . . . . . . . . . . . . . . . . . . . 41 ElianeGluckman 4 Banking of Corneas. . . . . . . . . . . . . . . . . . . . . . . . . . . 59 W. JohnArmitage 5 Banking of Heart Valves. . . . . . . . . . . . . . . . . . . . . . . . 69 RobertParker 6 Banking of Skin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 EllenHeck Part II Principles of 7 Storage, Processing and Preservation. . . . . . . . . . . . . . . . . 95 JohnN. Kearney 8 Cryopreservation. . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 DavidPegg 9 Sterilisation by Irradiation . . . . . . . . . . . . . . . . . . . . . . 123 ArturKaminski, IzabelaUhrynowska-Tyszkiewicz, andWaclawStachowicz Part III Ensuring Safety by 10 Testing the Donor. . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 AlanKitchenandJohnBarbara 11 Testing the Tissue and the Environment . . . . . . . . . . . . . . . 167 TedEastlundandMartellK. Winters vii viii Contents Part IV Ensuring Quality by 12 Establishing a Quality System. . . . . . . . . . . . . . . . . . . . . 191 ScottA. Brubaker 13 IT System. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217 LindaLodge Part V Legal and Ethical Environment 14 Regulatory and Ethical Issues. . . . . . . . . . . . . . . . . . . . . 231 DavidPegg Index . . . . .

• Format: Paperback
• Language: English
• ISBN: 9401785023
• ISBN13: 9789401785020
• Release Date: November 2014
• Publisher: Springer
• Length: 245 Pages
• Weight: 0.80 lbs.
• Dimensions: 0.5" x 6.1" x 9.2"