CRISPR-Cas system based diagnosis of infectious diseases

By Roohi Bansal

Since its discovery as a part of the bacterial defense mechanism, the Nobel Prize-winning technology CRISPR-Cas system has revolutionized the fields of genome editing and genetic engineering. Beyond gene-editing ability, scientists have leveraged its potential in the diagnosis of infectious diseases including COVID-19.

This book provides a detailed understanding of CRISPR-based rapid and point-of-care diagnostic kits like SHERLOCK, DETECTR, FELUDA, AIOD CRISPR-Cas12a, etc. for the diagnosis of infectious diseases including COVID-19; the importance of isothermal nucleic acid amplification processes like RPA and LAMP; and how the results of the CRISPR-based tests can be interpreted using paper-based lateral flow strips.

Because of the ease of performing the test and simple interpretation of the test results, CRISPR-based tests can be used at airports, ports, clinics, schools, etc., for better disease diagnosis, monitoring, management, and containment of infectious diseases like COVID-19.

Additionally, this book discusses Monoclonal Antibodies, which have revolutionized the treatment for cancer, arthritis, autoimmune diseases, etc. This book also talks about various strategies to isolate monoclonal antibodies from the COVID-19 recovered people and different ways to engineer these antibodies using hybridoma technology.

• Format: Paperback
• Language: English
• ISBN: 9354458300
• ISBN13: 9789354458309
• Release Date: March 2021
• Publisher: Roohi Bansal
• Length: 214 Pages
• Weight: 0.89 lbs.
• Dimensions: 0.6" x 6.0" x 9.0"