Correlative Light and Electron Microscopy: Volume 111

The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron micros? CLEM ) has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM, including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM.

• Format: Hardcover
• Language: English
• ISBN: 0124160263
• ISBN13: 9780124160262
• Release Date: August 2012
• Publisher: Academic Press
• Length: 460 Pages
• Weight: 2.75 lbs.
• Dimensions: 1.2" x 7.5" x 9.3"