Astrogliosis and Channel Function

By John V Zimmerman

Astrogliosis is a hallmark of central nervous system (CNS) neuroinflammatory disorders such as multiple sclerosis (MS). Astrocytes can play

both beneficial and detrimental roles in response to neuroinflammation, thus a detailed understanding of the underlying molecular mechanisms governing

astrogliosis might facilitate the development of therapeutic targets. While astrocytes do not express voltage-gated sodium channel (VGSC) Nav1.5 in

nonpathological human brain, they exhibit robust upregulation of Navi .5 within acute and chronic MS lesions

• Format: Paperback
• Language: English
• ISBN: 5215198675
• ISBN13: 9785215198674
• Release Date: January 2024
• Publisher: Mujeeb Publishers
• Length: 168 Pages
• Weight: 0.51 lbs.
• Dimensions: 0.4" x 6.0" x 9.0"