This book gives an overview of how microfluidic technologies transform tissue engineering and organ-on-chip (OoC) platforms. It introduces microfluidic and fluid dynamics principles and how microfluidic devices improve cell culture methodology, tissue development, and vascularization.
This volume focuses on organ-specific systems and their microfluidic platforms and offers an interdisciplinary view of tissue engineering. Chapters discuss the following systems heart-on-chip, neuron-on-chip, liver-on-chip, lung-on-chip, kidney-on-chip, gut-on-chip, and skin-on-chip. Each chapter provides detailed analysis on the design, fabrication, and application of these systems, emphasizing their ability to replicate the structure, function, and microenvironment of native tissues. Applications in drug discovery, disease modeling, and personalized medicine are explored extensively and emerging technologies, such as 3D bioprinting and multi-organ systems are discussed.
Aimed at researchers, professionals, and graduate students, this volume provides an interdisciplinary view of microfluidic technologies which sit at the intersection of microfluidics, biology, and material science.