This book explores the latest clinical research on how dietary supplements may extend healthy aging, or healthspan. As people age, their risk of developing age-related diseases, such as cardiovascular disease and neurodegenerative disorders, increases. These conditions often progress over time, leading to more profound consequences that diminish quality of life, cause significant suffering, and may even result in loss of dignity and independence. For decades, micronutrients, such as vitamins and minerals, have been recognized as essential for biological functions including antioxidation, energy production, and metabolism/synthesis of carbohydrates, lipids, amino acids, and other molecules. Furthermore, numerous preclinical studies in animals and cells have suggested that dietary supplements could potentially help prevent and treat age-related diseases. While some recent clinical studies on micronutrients have produced encouraging results, the overall findings have been mixed during the past. In this book, the author discusses advances in recent clinical research, with a focus on studies that have yielded relatively consistent outcomes. The highlighted clinical discoveries are also supported by preclinical evidence. Ultimately, this book aims to illuminate the clinical role of dietary supplements in combating age-related diseases and promoting a longer healthspan.
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