Direct Mechanisms in Cholesterol Modulation of Protein Function

By Justin Garson

Introduction.- Direct binding of cholesterol to proteins.- Cholesterol-recognition motifs in membrane proteins.- Molecular determinants of cholesterol binding to proteins: overview of crystallographic studies.- Crystallographic studies of steroid-protein interactions.- Insights into cholesterol binding sites in proteins from computational studies.- Cholesterol binding to NPC1/NPC2.- I Biophysical elements of the interaction between cholesterol and the nicotinic acetylcholine receptor.- Modulation of TRPV1 channels by cholesterol.- Cholesterol binding sites in inwardly rectifying potassium channels.

• Format: Paperback
• Language: English
• ISBN: 3030142671
• ISBN13: 9783030142674
• Release Date: August 2020
• Publisher: Springer
• Length: 168 Pages
• Weight: 0.57 lbs.
• Dimensions: 0.4" x 6.1" x 9.2"