Water and Biomolecules: Physical Chemistry of Life Phenomena

By Kunihiro Kuwajima

Book Overview

Mapping Protein Folding Landscapes by NMR Relaxation.- Experimental and Simulation Studies of the Folding/Unfolding of Goat ?-Lactalbumin.- Transition in the Higher-order Structure of DNA in Aqueous Solution.- Generalized-Ensemble Algorithms for Studying Protein Folding.- Protein Folding and Binding: Effective Potentials, Replica Exchange Simulations, and Network Models.- Functional Unfolded Proteins: How, When, Where, and Why?.- Structure of the Photointermediate of Photoactive Yellow Protein and the Propagation Mechanism of Structural Change.- Time-Resolved Detection of Intermolecular Interaction of Photosensor Proteins.- Volumetric Properties of Proteins and the Role of Solvent in Conformational Dynamics.- A Statistical Mechanics Theory of Molecular Recognition.- Computational Studies of Protein Dynamics.- Biological Functions of Trehalose as a Substitute for Water.- Protein Misfolding Diseases and the Key Role Played by the Interactions of Polypeptides with Water.- Effect of UV Light on Amyloidogenic Proteins: Nucleation and Fibril Extension.- Real-Time Observation of Amyloid Fibril Growth by Total Internal Reflection Fluorescence Microscopy.

• Format: Paperback
• Language: English
• ISBN: 3642100228
• ISBN13: 9783642100222
• Release Date: October 2010
• Publisher: Springer
• Length: 307 Pages
• Weight: 1.01 lbs.
• Dimensions: 0.7" x 6.1" x 9.2"