Virulence of Candida tropicalis: Experimental study

By G Hermann Jonas Tapsoba

Candida tropicalis is one of the most feared non-albicans C. species in the world (3 to 66% of isolates). The aim of the study was to assess the in vivo virulence of a telluric strain of C. tropicalis based on the G. mellonella model. The study was carried out in Burkina Faso.It was a prospective experimental study. Batches of 10 larvae of 280 to 320mg and a telluric strain of C. tropicalis identified by MALDI-TOF were used. Larvae were inoculated with 20μl of fungal suspension at increasing concentrations of 5,105, 1,106, and 5,106 CFU. A control group was injected with 20μL of sterile PBS. Melanisation and larval death were observed at 24 h over 12 days.In total, 100% of the larvae melanised 30 min after inoculation at concentrations of 1,106 and 5,106 CFU/larva and mortality was 100% at H48 (p

• Format: Paperback
• Language: English
• ISBN: 6208624630
• ISBN13: 9786208624637
• Release Date: February 2025
• Publisher: Our Knowledge Publishing
• Length: 52 Pages
• Weight: 0.18 lbs.
• Dimensions: 0.1" x 6.0" x 9.0"