Vascular Adhesion Molecules and Inflammation

By Jeremy D. Pearson

Book Overview

How early studies of inflammation led to our current views on the roles of vascular adhesion molecules.- Adhesion of leukocytes from flow: The selectins and their ligands.- Co-operative signaling between leukocytes and endothelium mediating firm attachment.- Production and presentation of chemokines by endothelial cells.- Platelet-activating factor: A signaling molecule for leukocyte adhesion.- Tight junctions and adherens junctions in endothelial cells: Structure and regulation.- The role of PECAM in leukocyte emigration.- Selective lymphocyte migration into secondary lymphoid rrgans and inflamed tissues.- Oxidation-reduction sensitive regulation of vascular inflammatory gene expression.- Quantification and imaging of vascular adhesion molecule expression in inflammatory diseases in vivo.- Leukocyte adhesion and activation in xenografts.- Control of leukocyte adhesion and activation in ischemia-reperfusion injury.- Control of leukocyte adhesion and activation in atherogenesis.

• Format: Hardcover
• Language: English
• ISBN: 3764358009
• ISBN13: 9783764358006
• Release Date: January 2000
• Publisher: Birkhauser Basel
• Length: 278 Pages
• Weight: 1.42 lbs.
• Dimensions: 0.7" x 6.7" x 9.6"