Recent advances in robot-assisted urologic surgery have significantly improved the quality of life for patients with prostate, bladder, and kidney cancers by enabling less-invasive procedures, reducing blood loss, and preserving functional outcomes. These developments may also influence diagnostic value; however, their overall impact remains insufficiently evaluated due to limited data and short follow-up periods. This Special Issue features state-of-the-art studies not only on robot-assisted urologic surgery but also on laparoscopic and transurethral approaches. It will undoubtedly be of great interest to all urologists.