Uptake and Trafficking of Protein Toxins

Book Overview

Two feet on the membrane: uptake of clostridial neurotoxins.- Receptors and binding structures for Clostridium difficile Toxins A and B.- Cell entry of C3 exoenzyme from Clostridium botulinum.- Receptor-binding and up-take of binary actin-ADP-ribosylating toxins.- Clostridial Binary Toxins: Basic Understandings that Include Cell-Surface Binding and an Internal "Coup de Grace".- Host cell chaperones Hsp70/Hsp90 and peptidyl-prolyl cis/trans isomerases are required for the membrane translocation of bacterial ADP-ribosylating toxins.- Multivalent Inhibitors of Channel-Forming Bacterial Toxins.- Toxin Transport by A-B Type of Toxins in Eukaryotic Target Cells and its inhibition by Positively Charged Heterocyclic Molecules.

• Format: Hardcover
• Language: English
• ISBN: 3319588915
• ISBN13: 9783319588919
• Release Date: December 2017
• Publisher: Springer
• Length: 256 Pages
• Weight: 1.21 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"