Despite the introduction of innovative technologies and accurate laboratory techniques, an adequate anamnesis still remains the most important tool to develop a correct diagnosis. When signs and symptoms described by patients are unusual, the correct identification of the disease becomes a very difficult challenge for clinicians. This book aims at providing support in the interpretation of the most unusual signs and symptoms that can be encountered in the clinical practice. Each sign is described in a concise way (one sign/one page): a full description of the symptoms as experienced by the patient is given, followed by its clinical meaning, the diagnosis, and therapeutic approach. The book collects thirty unusual symptoms that can be encountered by clinicians.
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