Tumor Cell Metabolism: Pathways, Regulation and Biology

Book Overview

Metabolic Remodeling in Bioenergetic Disorders and Cancer .- Tumor Cell Complexity and Metabolic Flexibility.- Autophagy and Tumor Cell Metabolism.-Tumour Hypoxia and the Hypoxia-Inducible Transcription.- MYC Regulation of Metabolism and Cancer.- Pyruvate Kinase M2: A Metabolic Tuner.- Role of the Pentose Phosphate Pathway in Tumour Metabolism.- Enzymes of the Tumour Metabolome in Diagnostic Applications.- Contribution of pH Alterations to the Tumor Microenvironment.- Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis? The Relevance of the Mitochondrial H+-ATP Synthase.- Canceromics Studies Unravel Tumor's Glutamine Addiction.- Essential Role of Mitochondria in Pyrimidine Metabolism.- Metabolic Fluxes in Cancer Metabolism.- Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer.

• Format: Hardcover
• Language: English
• ISBN: 3709118239
• ISBN13: 9783709118238
• Release Date: January 2015
• Publisher: Springer
• Length: 374 Pages
• Weight: 1.57 lbs.
• Dimensions: 0.9" x 6.1" x 9.2"