Tuberculosis: Clinical Management, Pathogenesis, Basic Science, and Public Health Perspectives, Second Edition

Tuberculosis remains one of the most enduring and consequential infectious diseases in human history. It is preventable, diagnosable, treatable, and curable; however, it continues to cause over a million deaths and immense suffering every year.

Since the first edition of this book, the field has changed substantially. TB can no longer be approached as a single clinical entity defined only by pulmonary disease and microbiological confirmation. It must be understood as a dynamic spectrum encompassing myriad factors as well as the lifelong consequences that may persist after microbiological cure.

Written and edited by experts in the field, this new collection from Cold Spring Harbor Perspectives in Medicine reflects the major scientific, clinical, diagnostic, therapeutic, public-health, and implementation advances of the past decade. This volume includes reviews of the global epidemiology of tuberculosis, its diagnosis and management, and updated accounts of both adult and pediatric tuberculosis. Subsequent chapters examine the complex immunological processes of the disease's pathology, biomarkers in tuberculosis, advances in the tuberculosis drug pipeline, and the interaction between tuberculosis and other conditions including HIV and diabetes mellitus.

This volume is intended for a wide readership: students at all institutions, clinicians caring for patients, nurses and allied health professionals, laboratory scientists, microbiologists, immunologists, pharmacologists, epidemiologists, trialists, program managers, policymakers, funders, advocates, community leaders, and experienced tuberculosis researchers seeking an integrated overview of progress and remaining gaps.

• Format: Hardcover
• Language: English
• ISBN: 162182540X
• ISBN13: 9781621825401
• Release Date: January 1
• Publisher: Cold Spring Harbor Laboratory Press
• Length: 650 Pages
• Dimensions: 2.0" x 7.0" x 10.0"