Two couples, each working through relationship issues, rent a gorgeous house in the desert for a sex and drug-fueled escape from reality. Sarah (Angela Trimbur) and Estelle (Janel Parrish) are longtime best friends looking forward to reconnecting after a period apart; their boyfriends, Joseph (Zach Avery) and Victor (Jonathan Howard), however, are immediately wary of one another. As tensions escalate over the course of a debaucherous night, things take an unexpected turn when a woman (Fairuza Balk) claiming to be a neighbor with car trouble shows up at the door. She seems harmless enough...or so they think.
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