Due to the advent of a number of new drugs with therapeutic promise, there has been an increased interest in the properties of 5-hydroxytryptamine (5-HT, serotonin). This book describes the major recent advances in this area, specifically with respect to the actions of 5-HT in the periphery. The scope is broad, covering 5-HT synthesis and catabolism, its receptors and their second messenger transduction systems, and the functional responses to 5-HT in peripheral tissues. Developments in the treatment of cardiovascular, gastrointestinal, and peripheral vascular disease are also discussed. Written by scientists actively working in the field, this book provides an extensive, authoritative, and up-to-date account of this important area of biomedical science.
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