The Neutrophil: The Natural Immune System

By J.G. Wheeler

Historically, the study of immunology has focused to a large extent on the central role of antigen recognition and antibody structure and function on the response of the host to infection. In the last two decades however, scientists have been turning their attention to the involvement of various cell types in host defense. Cells such as the macrophage, the natural killer cell, the neutrophil, and humoral factors comprise this innate or "natural" immune system. They can take part in various immune responses without prior sensitization, and have important modulatory effects on later, specific responses. This volume provides a collection of reviews written by leading scientists, covering a variety of topics relating to the biology and function of the neutrophil and its role in disease. A broad range of chapters include discussions of the neutrophil's basic cell biology and normal function, followed by specific examples of diseases resulting from neutrophil dysfunction and deficiency. The concepts in each chapter are brought to life through the use of clinical case studies. Advanced students and researchers in immunology, cell biology, and medicine will find The Neutrophil to be a valuable source of current research into this exciting field.

• Format: Paperback
• Language: English
• ISBN: 0199633738
• ISBN13: 9780199633739
• Release Date: July 1993
• Publisher: Oxford University Press
• Length: 332 Pages
• Weight: 1.25 lbs.
• Dimensions: 9.3" x 0.7" x 6.1"