The Neuron: Cell and Molecular Biology

By Irwin B. Levitan, Leonard K. Kaczmarek, Kaczmarek Levitan, et al.

Book Overview

The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a single neuron generates varied patterns of electrical activity. Next are covered the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter and hormones at synaptic junctions between neurons. The second part of the book covers the biochemical pathways that are linked to the action of neurotransmitters and that can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory.
New for the Third Edition: This is a thoroughly revised and expanded edition (60 pages longer) and features a new 8-page, 4-color insert as well as the following changes:
1. The mapping of the human genome and that of other species has led to the discovery of numerous new proteins that regulate the excitability, development, and function of neurons. These have been incorporated into the new edition in nearly all of the chapters.
2. The first section of the book, which deals with neuronal excitability, has been reorganized to make it more readable for those students with less background in physical sciences. A new chapter has been added to this section to allow the incorporation of new information on ion channel structure and on the role of channel auxiliary proteins in modulating neuronal excitability.
3. A new chapter, "The Birth and Death of Neurons," has been added to the last section. In addition to covering new discoveries about the early development of neurons, this chapter describes the recent discovery that new neurons are continually being formed in certain parts of the adult mammalian brain. It also describes research on stem cells, which holds therapeutic potential for the repair of damaged or diseased brain tissue.
4. The use of imaging technologies in the study of the brain has expanded enormously in the past few years. The new edition describes some of these new approaches. Moreover, the introduction of full color plates now allows many new images to be presented in their original form.

• Format: Hardcover
• Language: English
• ISBN: 0195145224
• ISBN13: 9780195145229
• Release Date: November 2001
• Publisher: Oxford University Press
• Length: 632 Pages
• Weight: 2.90 lbs.
• Dimensions: 6.5" x 1.6" x 9.0"

Customer Reviews

Great book for my cellular biology of the nervous system class

Excellent textbook, explains very well the terms it presents while on the same time is a very easy to read book. It seemed much easier for me to read and comprehend what we learned in class with "the Neuron" in comparison to our designated textbook, which was also very good but less enjoyable.

Great book

I've really enjoyed this book so far. It's by far the best neuro molec book out that I've got my hands on.

Neuron details

The molecular biology of the neuron is considered, from its electrical properties, synapses, differentiation, axon pathfinding, to chapters concluding with behavior and memory. Well written and includes easy to follow schematic diagrams, this reference is suitable for the motivated general reader.

Great book on all levels

"The Neuron" was a fantastic book to read. It served as a perfect mesh between a textbook and a novel. The book was written in plain english so anyone could enjoy it. The concepts discussed ranged from elementary to advanced which provided a nice progression to more complicated things. This book is a must read for anyone interested in neuroscience.

Very readable

I have compared several neurobiology textbooks and this one is my favorite. It's almost like a novel, very enjoyable. It emphasizes understanding of important concepts rather than throwing an overwhelming amount of facts at the students. And the organization of the material is great. There is an updated edition now, and I look forward to reading it.