The Inflammasomes

By Isabelle Couillin

Book Overview

Molecular definition of inflammasomes.- Pyroptosis: A Caspase-1-dependent programmed cell death and a barrier to infection.- Activation of the inflammasome by bacterial pathogens.- The Role of Inflammasomes in Viral Infection.- Inflammasome activation in response to eukaryotic pathogens.- Inflammasome activation by pathogenic crystals and particles.- Inflammasome activation by danger signals.- Toll like receptors and inflammasomes.- Inflammasome in the skin.- Cancer, inflammasomes and adjuvanticity.- Inflammasome and lung pathologies.- Mechanisms of NLRP3 inflammasome activation in CAPS patients.- Activation and regulation of the NLRP3 inflammasome.- Treatment of inflammasome-related disorders.

• Format: Paperback
• Language: English
• ISBN: 3034803435
• ISBN13: 9783034803434
• Release Date: November 2013
• Publisher: Springer
• Length: 226 Pages
• Weight: 0.75 lbs.
• Dimensions: 0.6" x 6.1" x 9.0"