The Biology of Germinal Centers in Lymphoid Tissue

By G. Jeanette Thorbecke

Book Overview

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.

• Format: Hardcover
• Language: English
• ISBN: 3540645594
• ISBN13: 9783540645597
• Release Date: November 1998
• Publisher: Springer
• Length: 241 Pages