Aging is associated with morphologic and functional alterations of organ systems including the genitourinary tract. Aging of the bladder leads to urgency, frequency, dysuria, recurrent urinary tract infections and incontinence both in aging men and women. Understanding the morphologic and functional processes of the aging bladder may decrease symptoms, costs and help to develop new, preventive strategies for the treatment of the aging bladder. This book reviews the present knowledge of morphologic and functional alterations of the aging bladder, providing new insights to optimize therapeutic options for the treatment of the aging bladder in daily practice.