High Quality Content by WIKIPEDIA articles Thalidomide ( /θəˈlɪdəmaɪd/) was introduced as a sedative drug in the late 1950s that was typically used to cure morning sickness. In 1961, it was withdrawn due to teratogenicity and neuropathy. There is now a growing clinical interest in thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. The drug is a potent teratogen in zebrafish, chickens, rabbits and primates, including humans; severe birth defects have been reported at an exceptional level in individuals whose mother took the drug during pregnancy.
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