In this book we have established a novel series of 2-(2-chlorophenyl)quinoline-4-carboxylic acid based thiosemicarbazide derivatives all compounds are conforming by their physical data (melting point) and spectral data (Mass analysis, 1H NMR, 13C NMR). All compounds are analyzing in antibacterial and antifungal Biological activity. In biological analysis we have found that many compounds have potent activity against different strains.
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