This Special Issue aims to deepen the understanding of suicidal behaviors (SBs), as well as their risk and protective factors, and to highlight innovative approaches to intervention, prevention, and postvention. The collected contributions illustrate the multifaceted nature of suicidality, addressing its psychological, social, and contextual dimensions across diverse populations and life stages. Empirical studies examine the impact of various forms of violence on SBs in Mexico, psychopathological networks in individuals with and without suicidal ideation, and the concurrent validity of digital tools for risk assessment. Research focusing on adolescents explores the interplay between regulation strategies, contextual stressors, addictions, and suicidality. Preventive strategies are also considered, including measures targeting high-risk locations, the influence of social bonds within military units, and suicide prevention efforts in older veterans. Additionally, systematic reviews synthesize evidence on grief interventions for suicide loss survivors, the role of social cognition in psychosis, and the mechanisms linking defeat, entrapment, and depression to suicidal ideation in youth. A sociological perspective further situates suicidality within the post-COVID-19 context in Spain. Together, these contributions provide a comprehensive and integrative outlook that enriches our understanding of SBs and informs tailored, evidence-based strategies to reduce their burden.