Stat1

High Quality Content by WIKIPEDIA articles STAT1 is a member of the Signal Transducers and Activators of Transcription family of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type I, type II or type III interferons. In response to IFN-γ stimulation, STAT1 forms homodimers or heterodimers with STAT3 that bind to the GAS (Interferon-Gamma Activated Sequence) promoter element; in response to either IFN-α or IFN-β stimulation, STAT1 forms a heterodimer with STAT2 that can bind the ISRE (Interferon Stimulated Response Element) promoter element. In either case, binding of the promoter element leads to an increased expression of ISG (Interferon Stimulated Genes).

• Format: Paperback
• Language: English
• ISBN: 5512208500
• ISBN13: 9785512208502
• Release Date: January 1
• Publisher: Book on Demand Ltd.
• Length: 144 Pages
• Weight: 0.40 lbs.
• Dimensions: 0.3" x 5.8" x 8.3"