Sirt6 Activities in DNA Damage Repair and Premature Aging: Functions of Sirt6

By Shrestha Ghosh

Book Overview

Introduction.- Materials and Methods.- Results-I. Lamin A is an endogenous activator of SIRT6 in DNA damage repair process.- Results-II. Haploinsufficiency of p53 rescues lifespan and premature aging-associated abnormalities in Sirt6-deficient mice.- Results-III. SIRT6 is an acetylated protein and a NAD+-dependent self-deacetylase.- Discussion.

• Format: Paperback
• Language: English
• ISBN: 9813292695
• ISBN13: 9789813292697
• Release Date: September 2020
• Publisher: Springer
• Length: 151 Pages
• Weight: 0.63 lbs.
• Dimensions: 0.4" x 6.1" x 9.2"