Serotonergic Psychedelics: Molecular Mechanisms and Therapeutic Potential explores how psychedelic compounds influence the brain, consciousness, emotion, and behaviour through serotonin receptors, particularly 5-HT2A. It examines the chemistry, pharmacology, metabolism, neural signalling, neuroplasticity, and psychoplastogenesis associated with tryptamines, ergolines, phenethylamines, and ayahuasca. The book reviews emerging clinical evidence for depression, anxiety, addiction, and existential distress while distinguishing established findings from preliminary hypotheses. It also discusses structured psychological support, therapeutic procedures, safety concerns, HPPD, seizure risk, drug interactions, repeated exposure, ethical issues, and regulation. By integrating molecular neuroscience, pharmacology, clinical research, and therapeutic practice, the book presents a balanced account of psychedelic science, its therapeutic promise, its limitations, and the questions that future research must address.
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