1. From Bedside to Bench: How Clinical Reality Should Instruct Stroke Modeling Pauline Patak and Dirk M. Hermann 2. How to Avoid Bumping into the Translational Roadblock Malcolm Macleod 3. Modeling Focal Cerebral Ischemia in Rodents: Introduction and Overview Vincent Prinz and Matthias Endres 4. Focal Cerebral Ischemia in the Mouse and Rat Using the Intraluminal Suture-Filament Model Ludmila Belayev, Matthias Endres, and Vincent Prinz 5. Focal Ischemia Models: Middle Cerebral Artery Occlusion Induced by Electrocoagulation, Occluding Devices, and Endothelin-1 I. Mhairi Macrae 6. Rodent Models of Thromboembolic Stroke Cyrille Orset, Benoit Haelewyn, Kilian Vivien, Denis Vivien, and Alan R. Young 7. Photochemical and Endothelin Models of Focal Brain Ischemia Otto W. Witte 8. Housing in an Enriched Environment: A Tool to Study Functional Recovery after Experimental Stroke Karsten Ruscher and Tadeusz Wieloch 9. Modeling Risk Factors and Confounding Effects in Stroke Barry McColl, David Howells, Nancy Rothwell, and Adam Denes 10. Effect of Anesthesia in Stroke Models Richard J. Traystman 11. Non-Invasive Brain Imaging in Small Animal Stroke Models: MRI and PET Anna M. Planas 12. Noninvasive Optical Imaging in Small Animal Models of Stroke Andreas Wunder and Jan Klohs 13. Behavioral Testing in Mouse Models of Stroke Mustafa Balkaya and Matthias Endres 14. Behavioral Testing in Rodent Models of Stroke Gerlinde A. Metz 15. Histology and Infarct Volume Determination Clemens Sommer 16. Ethics of Modeling of Cerebral Ischemia in Small Animals Ute Lindauer 17. Quality Control and Standard Operating Procedures Ulrich Dirnagl 18. Statistics in Experimental Stroke Research: From Sample Size Calculation to Data Description and Significance Testing Ulrich Dirnagl 19. Complexities, Confounders, and Challenges in Experimental Stroke Research: A Checklist for Researchers and Reviewers Ulrich Dirnagl
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