Ribosome-Inactivating Proteins: Ricin and Related Proteins

This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.

• Format: Hardcover
• Language: English
• ISBN: 1118125657
• ISBN13: 9781118125656
• Release Date: June 2014
• Publisher: Wiley-Blackwell
• Length: 328 Pages
• Weight: 1.76 lbs.
• Dimensions: 0.8" x 6.9" x 9.7"