This issue comprises concise reviews, by international experts, of the state of the art and advances in their fields. The subjects reviewed have been chosen from both common and less common diseases among the serious relapsing inflammatory rheumatic disorders. They range from RA, through SLE and APS, to primary vasculitis and Behcet's. They have all been chosen as areas where new knowledge should affect the way we approach and manage rheumatic disease in the clinic. The reviews should be relevant to the rheumatologist when wrestling with the frequent problems of chronic persistent arthritis as well as with the systemic disease that can cause life-threatening problems in all these disorders.
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