Research Protocols for Ophthalmic Disease Mechanisms and Therapeutics: Glaucoma - Ocular Hypertension

By Najam A. Sharif

Research Protocols for Ophthalmic Disease Mechanisms and Therapeutics: Glaucoma - Ocular Hypertension offers a detailed, step-by-step protocols for isolating, characterizing, and analyzing cells and tissues of the eye's anterior segment-where OHT originates-using techniques from molecular biology, pharmacology, and histology.

Across eight thematic sections, the book covers ocular anatomy, drug screening, receptor localization, cell-based assays, in vitro and in vivo models, drug formulation, and cutting-edge technologies such as gene editing, single-cell RNA sequencing, and stem cell therapies. Each protocol is designed to support reproducibility and translational relevance.

Key Features:

- Details validated protocols for drug discovery and disease modeling.
- Demonstrates methods for studying receptor function and pharmacokinetics.
- Provides animal models and ex vivo systems to evaluate therapeutic strategies.
- Incorporates emerging tools such as CRISPR, metabolomics, and exosomes.
- Bridges experimental design with clinical relevance for glaucoma research.

• Format: Paperback
• Language: English
• ISBN: 9815324357
• ISBN13: 9789815324358
• Release Date: August 2025
• Publisher: Bentham Science Publishers
• Length: 618 Pages
• Weight: 3.70 lbs.
• Dimensions: 1.6" x 8.0" x 10.0"