Renal Fibrosis: Mechanisms and Therapies

By Bi-Cheng Liu

Book Overview

Prevalence and burden of chronic kidney disease.- Pathomorphism and evaluation of renal fibrosis.- Endothelial cells and renal fibrosis.- Mesangial cells and renal fibrosis.- Podocyte injury and glomerular sclerosis.- Tubular epithelial cell injury and renal fibrosis.- Monocyte-macrophages and renal fibrosis.- Pericytes and renal fibrosis.- Myofibroblast: Origin and regulation in renal fibrosis.- Mitochondrial lesion and renal fibrosis.- Metabolic nuclear receptors and renal fibrosis.- Role of renin angiotensin system in renal fibrosis.- Role of aldosterone in renal fibrosis.- TGF-β1 and renal fibrosis.- Connective tissue growth factor and renal fibrosis.- Lipid metabolism disorder and renal fibrosis.- Renal interstitial lymphangiogenesis in renal fibrosis.- Cell apoptosis and autophagy in renal fibrosis.- Pyroptosis and renal fibrosis.- Cell cycle arrest and renal fibrosis.- Inflammatory mediators and renal fibrosis.- Role of inflammasome in chronic kidney disease.- Oxidative stress and renal fibrosis.- Hypoxia and renal tubulointerstitial fibrosis.- Proteinuria and progression of chronic kidney disease.- Hypertension and renal fibrosis.- Diabetic Kidney disease and renal fibrosis.- Chronic allograft nephropathy and renal fibrosis.- Polycystic kidney disease and renal fibrosis.- Acute kidney injury and renal fibrosis.- Senescence and renal fibrosis.- Urinary biomarkers of renal fibrosis.- New therapies for the treatment of renal fibrosis.

• Format: Paperback
• Language: English
• ISBN: 9811388733
• ISBN13: 9789811388736
• Release Date: August 2020
• Publisher: Springer
• Length: 709 Pages
• Weight: 2.21 lbs.
• Dimensions: 1.4" x 6.1" x 9.2"