ZARA ROSSI quietly closes the door behind her and tiptoes into the Ancient Manuscripts Room in the Papal Archives in Rome. The young American Ph.D. candidate seeks information for her dissertation and surveys the scene, yearning to join the world's elite scholars. Disheartened after a seemingly unsuccessful day hunting for little-known information about Henry VIII's abdication from the Roman Church, she prepares to depart. But in the final moments before closing, Zara stumbles upon a letter, hidden for centuries. A desperate warning, scrawled upon crumbling parchment, informs Pope Clement VII of imminent disaster and reveals a conspiracy depicted by a stunning portrait: one that alters history.
Hoping to prove herself worthy of respect and love, Zara searches for the masterpiece, and begins to amass clues which reveal the painting's extraordinary tale...