Pioneering Stem Cell/Gene Therapy Trials

By Roger Bertolotti

The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion.

• Format: Hardcover
• Language: English
• ISBN: 9067643947
• ISBN13: 9789067643948
• Release Date: February 2004
• Publisher: CRC Press
• Length: 330 Pages
• Weight: 1.70 lbs.
• Dimensions: 0.8" x 6.4" x 9.7"