Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals

By: International Atomic Energy Agency

Since their clinical use initiation in the 1970's, Fluorine-18 (F-18) radiopharmaceuticals continue to play an important role in nuclear medicine. It is therefore essential to make available broad information on practical production routes and optimal quality control for F- 18 tracers, to achieve the best possible products in high quantity and quality for clinical applications while fulfilling all regulatory requirements. This publication describes the chemical and biological properties of F-18 radiopharmaceuticals. This includes aspects relating to F-18 target production and radiofluorination methods, with focus on the applied techniques. The publication presents a disease oriented approach, describing F-18 radiopharmaceuticals, ranging from the physiological/biological aspects to dedicated radiopharmaceutical development approaches and provides readers with clear guidelines and methods for the production of F-18 radiopharmaceuticals.

• Format: Paperback
• Language: English
• ISBN: 9201227213
• ISBN13: 9789201227218
• Release Date: February 2022
• Publisher: International Atomic Energy Agency
• Length: 166 Pages
• Weight: 1.04 lbs.
• Dimensions: 0.4" x 8.3" x 11.7"