This text provides an understanding of the genetic sciences underpinning the development of modern drugs and explains the genetic and environmental bases of variability in human response to those drugs. It does so through an unraveling of the core scientific principles and careful choice of illustrative examples drawn from the current literature. Principally written for all those with an interest in pharmacogenetics, including pharmacologists, pharmacists, drug developers in the pharmaceutical industry and drug regulators, the evidence-based perspective adopted should also provide a valuable text for undergraduates in pharmacy and clinical pharmacology.
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