Preparation and characterization of ibuprofen co-crystals

By Alpana Kulkarni

Literature survey has indicated that majority of the co-crystals of ibuprofen were prepared with low molecular weight coformers. In the present study, it was demonstrated that ibuprofen forms co-crystals with high molecular weight coformers like povidone K- 25 and K-30. We have successfully achieved two objectives.1. Improvement in solubility of ibuprofen by formation of co-crystals of ibuprofen: povidon.2. Improvement in analgesic activity of ibuprofen by formation of co-crystals of ibuprofen: povidon.

• Format: Paperback
• Language: English
• ISBN: 3330023651
• ISBN13: 9783330023659
• Release Date: June 2020
• Publisher: LAP Lambert Academic Publishing
• Length: 100 Pages
• Weight: 0.35 lbs.
• Dimensions: 0.2" x 6.0" x 9.0"