Skin Structure and Physiology.- Methods for the Measurement of Percutaneous Absorption.- Mathematical Treatments and Early Models of Skin Permeability.- "Building error upon error" The New Breadth of Research in the Field.- Algorithms for Estimating Permeability Across Artificial Membranes.- Other Approaches to Modelling Percutaneous Absorption.- "Squiggly lines and random dots - you can fit anything with a non-linear model".- Finite-dose models of transient exposures and volatile formulation components.- "The Devil Is in the Detail ...".- Conclusions and Recommendations for Model Development and Use.
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